There is abundant information on Brest Litovsk on the Internet and in every library on Brest Litovsk (aka Brisk and many other names), since it’s been an important city for centuries. Here are some links that provide a more specifically Jewish perspective:
The Brest-Belarus Group Website For descendants and genealogical researchers. Some interesting historical information, especially about specific families and individuals, although it hasn’t been updated in a while and the list-serve seems more or less defunct, according to the coordinator.
YIVO article “Brest” Good history from the first days of Jewish settlement in the 14th century.
1918 Treaty of Brest Litovsk on Wikipedia
“Brest Litovsk” from the Jewish Virtual Library
The city of Brest, Belarus on Wikipedia
Ten Facts You May Not Know About Brisk & Briskers is a lively, idiosyncratic overview of both the ancient and modern history of Brisk, with some excellent photos and updated information on the current Jewish community.
The Jewish Community of Brisk from Beit HaTfutsot, the Museum of the Jewish People in Israel.